Montmorillonit-Gümüş Partikülünün Antibakteriyel Özelliği ve Kullanımı

Montmorillonitin gümüş partikülleriyle sentezlenmesi ve oluşan yeni yapının antibakteriyel özelliklerinin incelendiği yakın tarihli bir çalışmada;

Montmorillonit-Gümüş partikülü başarı ile sentezlenmiş ve sentezlenen yapının Gram Pozitif (S.Aureus, metisilin dirençli S.Aureus-MRSA) ile Gram Negatif ( E.Coli, E.Coli-O157:H7, Klebsiella Pneumoniae) Bakterilerine karşı (özellikle de küçük gümüş nano partiküllü yapıların) çok ciddi bir biçimde yüksek antibakteriyel özellik gösterdiği belirlenmiştir. Makale sonunda, Montmorillonit-gümüş partiküllerinin tıp uygulamaları için uygulanabilir olduğu belirtilmiştir.

Çalışmanın İngilizce özetine aşağıda yer verilmiştir

Synthesis Of Silver Nanoparticles İn Montmorillonite And Their Antibacterial Behavior.
Shameli K, Ahmad MB, Zargar M, Yunus WM, Rustaiyan A, Ibrahim NA.
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
PMID: 21674015 [PUBMED – indexed for MEDLINE] Int J Nanomedicine. 2011;6:581-90
Silver nanoparticles (Ag NPs) were synthesized by the chemical reducing method in the external and interlamellar space of montmorillonite (MMT) as a solid support at room temperature. AgNO(3) and NaBH(4) were used as a silver precursor and reducing agent, respectively. The most favorable experimental conditions for synthesizing Ag NPs in the MMT are described in terms of the initial concentration of AgNO(3). The interlamellar space limits changed little (d-spacing = 1.24-1.47 nm); therefore, Ag NPs formed on the MMT suspension with d-average = 4.19-8.53 nm diameter. The Ag/MMT nanocomposites (NCs), formed from AgNO(3)/MMT suspension, were characterizations with different instruments, for example UV-visible, PXRD, TEM, SEM, EDXRF, FT-IR, and ICP-OES analyzer. The antibacterial activity of different sizes of Ag NPs in MMT were investigated against Gram-positive, ie, Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) and Gram-negative bacteria, ie, Escherichia coli, Escherichia coli O157:H7, and Klebsiella pneumoniae, by the disk diffusion method using Mueller-Hinton agar (MHA). The smaller Ag NPs were found to have significantly higher antibacterial activity. These results showed that Ag NPs can be used as effective growth inhibitors in different biological systems, making them applicable to medical applications.